Most school districts in the Puget Sound area have already announced early closures.
How much snow and freezing rain a region receives falls will depend on the exact track of the low pressure system.
In Washington, about 50,000 people lost power.
Washington's Governor, Jay Inslee, declared an emergency across the state on Friday.
The sun was out on Sunday morning but the National Weather Service says snow will return late in the afternoon into the evening across the Northwest.
Strong winds will accompany the system and produce blowing snow, especially in rural open areas.
According to Yuhas, a winter storm watch will be in effect for most of the Twin Cities.More news: Alicia Keys says 2019 Grammys will be the "sickest" yet
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A winter storm likely will bring snow to the Treasure Valley on Friday night and is expected to drop snow all weekend, according to the National Weather Service. Snow will then likely continue through the night and through most of Tuesday, though at least brief lulls will be possible.
In Portland, a tanker truck blocked a ramp for hours after sliding into a vehicle on an interchange between Interstates 5 and 84. A California man died in rough waters off of Maui on Friday, Hawaii News Now reported.
The central and southern metro are included in the advisory where there is the best chance to see 3 inches or more of accumulation, but I wouldn't be surprised to see even the north metro come away with 3 or so inches.
Pacific Northwest residents who are more accustomed to rain than snow are digging out from a winter storm and bracing for more.
Autumn Sang was at a mobbed grocery store in Tualatin, Oregon, on Friday stocking up for the coming storm for herself and her neighbor, who is disabled and doesn't have a vehicle.
But more snow was possible for the region by midweek, the report said. It's like, 'Use your brain!